Jazz Pharmaceuticals' Ziihera plus chemotherapy cuts death risk 24% in Phase 3 gastroesophageal cancer trial
Bitget2026/10/23 14:16- Jazz Pharmaceuticals presented updated Phase 3 Ziihera survival results in first-line HER2-positive advanced gastroesophageal adenocarcinoma at ESMO 2026.
- Ziihera with chemotherapy significantly improved overall survival versus trastuzumab with chemotherapy.
- Adding tislelizumab sustained survival benefits versus trastuzumab with chemotherapy, but did not significantly improve survival over Ziihera with chemotherapy.
- Safety profiles remained unchanged with longer follow-up.
- The FDA cleared both Ziihera regimens on August 25, 2026, for first-line treatment in specified HER2-positive patient groups.
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