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Rapport Therapeutics Says Bipolar Mania Drug Meets Phase 2 Primary Endpoint; Shares Rise

Rapport Therapeutics Says Bipolar Mania Drug Meets Phase 2 Primary Endpoint; Shares Rise

MT newswireMT newswire2026/10/20 11:21
07:21 AM EDT, 10/20/2026 (MT Newswires) -- Rapport Therapeutics (RAPP) shares rose more than 29% in Tuesday premarket trading after the company said its experimental drug RAP-219 met the primary endpoint in a phase 2 trial for acute bipolar mania. The company said the drug achieved a 3.1-point placebo-adjusted improvement in the Young Mania Rating Scale at week 3. RAP-219 was generally well-tolerated, with no serious adverse events reported during the three-week treatment period, the company said. Rapport Therapeutics said it plans to meet with the Food and Drug Administration in Q1 2027 to discuss the data and that two phase 3 trials expected to begin in H2 2027.
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